Professor Joseph Jao Yiu SUNG (沈祖堯教授)

Fellow of Royal Australian College of Physicians
Fellow of American College of Gastroenterology (USA)
Fellow of Royal College of Physicians (London)
Doctor of Medicine (CUHK)
Fellow of Royal College of Physicians (Edinburgh)
Fellow of Hong Kong Academy of Medicine (HK)
Fellow of Hong Kong College of Physicians (HK)
Doctor of Philosophy (Canada)
Member of the Royal College of Physician (UK)
Bachelor of Medicine and Bachelor of Surgery (HK)  


Founding Director and Advisor, Stanley Ho Centre for Emerging Infectious Diseases, School of Public Health and Primary Care
Professor of Medicine and Therapeutics, Department of Medicine and Therapeutics
Chairman, Department of Medicine and Therapeutics
Associate Dean (General Affairs), Faculty of Medicine 
Head, Shaw College of the University


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Having received his MBBS from The University of Hong Kong in 1983, Professor Joseph Sung obtained Doctor of Philosophy from the University of Calgary and Doctor of Medicine from The Chinese University of Hong Kong in 1992 and 1997 respectively. He has held fellowships from the Royal College of Physician of Edinburgh, London, Thailand & Glasgow; American College of Gastroenterology; Royal Australian College of Physicians; American Gastroenterological Association; Hong Kong College of Physicians and Academy of Medicine.

Professor Sung has published over 350 full scientific articles in the foremost journals and also has reviewed more than 15 prestigious journals. His contributions to the advancement of medical sciences and academic development have been recognized with awards such as Outstanding Staff and Team Award (Hospital Authority, 1998); Leader of the Year 2001: Innovation and Technology (Sing Tao Daily and Hong Kong iMail); Eminent Scientist of the Year 2003 (the International Research Promotion Council, 2003); Asian Hero (Time Magazine, 2003); Distinguished Award for Scientist and Medical Profession in the Fight Against SARS (RTHK and Ming Pao Hong Kong, 2003); Vice Chancellor's Exemplary Teaching Award (CUHK, 2003); Croucher Senior Medical Research Fellowship (Croucher Foundation, 2004); Silver Bauhinia Star (Government of Hong Kong Special Administrative Region, 2004); and Cheung Kong Achievement Award (Ministry of Education of China and Li Ka Shing Foundation, 2006). 

• Viral Hepatitis and Hepatocellular Carcinoma
• Enteric Infections including Viral and Protozoa Infections of the DigestiveTract
• Severe Acute Respiratory Syndrome
• HIV/AIDS

Sung JJY, Chan HLY, Wong ML, Bowden S, Liew CT, Hui AY, Wong VWS, Leung NWY. Lcarinini Intrahepatic Load of Hepatitis B Virus Covalently Closed Circular DNA can be a Predictor of Sustained Response to Therapy. Gastroenterol (in press)

Xin Wang, Yangchao Chen, Quan-bin Han, Chu-yan Chan, Hua Wang, Zheng Liu, Christopher Hon-ki Cheng, David T. Yew, Marie CM Lin, Ming-liang He, Hong-xi Xu, Joseph JY Sung, Hsiang-fu Kung . Proteomic Identification of Molecular Targets of Gambogic Acid: Role of Stathmin in Hepatocellular Carcinoma, Proteomics (in press)

Chan Lik Yuen Henry; Tse Mei Ling; Chim Mei Ling Angel; Wong Wai Sun Vincent; Choi Cheung Lung Paul; Yu Jun; Zhang Mingdong and Sung Joseph Jao Yiu. Association of cytokine gene polymorphisms and liver fibrosis in chronic hepatitis B. Journal of Gastroenterology and Hepatology May 2008; 23(5):783-789

WY Lam, Julian W Tang, Apple CM Yeung, Lawrence CM Chiu, Joseph JY Sung, Paul KS Chan. Avian Influenze virus A/HK/483/97 (H5N1) NS1 protein induces apoptosis in human airway epithelial cells. Journal of Virology Mar 2008; 82(6):2741-2751

N Lee, CK Wong, PKS Chan, SWM Lun, G Lui, B Wong, DSC Hui, CWK Lam, CS Cockram, KW Choi, ACM Yeung, JW Tang, JJY Sung. Hypercytokinermia and Hyperactivation of phosphor-p38 mitogen-activated protein kinase in severe human influenza A virus infection. Clinical Infectious Diseases Sept 15 2007; 45:723-731

Yangchao Chen, Marie Chia-mi Lin, Hua Wang, Chu-yan Chan, Lei Jiang, Sai Ming Ngai, Jun Yu, Ming-liang He, Pang-chui Shaw, David T. Yew, Joseph J Sung and Hsiang-fu Kung. Proteomic analysis of EZH2 downstream target proteins in hepatocellular carcinoma. Proteomics Sep 2007; 7(17):3097-3104

Man SY, Lee N, Ip M, Antonio GE, Chau SSL, Mak P Graham, CA Zhang, M Liu G, Chan PKS, Ahuja AT, Hui D, Sung JJY, and Rainer TH. Prospective comparison of three predictive rules for assessing severity of community acquired pneumonia in Hong Kong. Thorax April 2007; 62:348-353

Ignatius T Yu, Zhan Hong Xie, Kelin K. Tsoi, Yuk Lan Chiu, Siu Wai Lok, Xiao Ping Tang, David S. Hui, Nelson Lee, Yi Min Li, Zhi Tong Huang, Tao Liu, Tze Wai Wong, Nan Shan Zhong, and Joseph J. Sung. Why Did Outbreaks of Severe Acute Respiratory Syndrome Occur in Some Hospital Wards but Not in Others? Clinical Infectious Diseases April 2007; 44(8):1017-1025

Richard KT Kam, Terence CW Poon, Henry LY Chan, Nathalie Wong, Alex Y Hui, Joseph JY Sung. High-throughtput quantitative profiling of serum N-glycome by MALDI-TOF mass spectrometry and N-Glycomic fingerprint of liver fibrosis. Clinical Chemistry 2007; 53(7):1254-1263

Julian W Tang Ka Fai To, Anthony WI Lo, Joseph JY Sung, HK Ng, Paul KS Chan. Quantitative temporal-spatial distribution of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) in post-mortem tissues. Journal of Medical Virology 2007; 79:1245-1253

Chen Y, Lin MC, Yao H, Wang H, Zhang AQ, Yu J, Hui CK, Lau GK, He ML, Sung J, Kung HF. Lentivirus-mediated RNA interference targeting EZH2 inhibits hepatocellular carcinoma growth via down-regulation of stathmin. Hepatology 2007; 46:200-208

Chan MC, Sung JJ, Lam RK, Chan PK, Lai RW, Leung WK. Sapovirus detection by quantitative real-time RT-PCR in clinical stool specimens. J Virol Methods Jun 2006; 134(1-2):146-153

Julian W. Tang, Jo L. K. Cheung, Ida M. T. Chu, Joseph J. Y. Sung, Malik Peiris, and Paul K. S. Chan. The Large 386-nt Deletion in SARS-Associated Coronavirus: Evidence for Quasispecies? The Journal of Infectious Diseses 15 Sep 2006; 194:808-813

DTM Leung, WWC van Maren, FKL. Chan, WS Chan, AWI Lo, CH Ma, FCH. Tam, KF To, PKS Chan, JJY Sung, and PLLim. Extremely Low Exposure of a Community to Severe Acute Respiratory Syndrome Coronavirus; False Seropositivity due to Use of Bacterially Derived Antigens. Journal of Virology Sep 2006; 80(18):8920-8928

Kenneth Tong, He Ming-Liang, Kung Hsiang-fu, Joseph Sung, Lee Shui Shan. The implications of a high allelic frequency of CYP2B 6 G516T in ethnic Chinese persons. Clinical Infectious Diseases 15 August 2006; 43:541-542

Poccia F, Agrati C, Castilletti C, Bordi L, Gioia C, Horejsh D, Ippolito G, Chan PK, Hui DS, Sung JJ, Capobianchi MR, Malkovsky M. Anti-Severe Acute Respiratory Syndrome Coronavirus Immune Responses: The Role Played by V gamma 9V delta 2 T Cells. J Infect Dis 2006; 193:1244-1249

Lee N, Rainer TH, Ip M, Zee B, Ng MH, Antonio GE, Chan E, Lui G, Cockram CS, Sung JJ, Hui DS. The role of laboratory variables in differentiating SARS-coronavirus from other causes of community-acquired pneumonia in hospitalized patients within the first 72 hours. Eur J Clin Microbiol Infect Dis 2006; 25:765-772.

Ronald TK Pang, Terence CW Poon, KC Allen Chan, Nelson LS Lee, Rossa WK Chiu, Yu Kwan Tong, Ronald MY Wong, Stephen SC Chim, Sai M Ngai, Joseph JY Sung, and YM Dennis Lo. Serum Proteomic Fingerprints of Adult Patients with Severe Acute Respiratory Syndrome. Clinical Chemistry 2006; 52(3):421-429

Chan HLY, Tse A, Zhang M, Wong V, Chim A., Hui A., Sung, JJ. Polymorphism of interleukin-1beta in association with sustained virological response to anti-viral treatment in chronic hepatitis B in Chinese. Alimentary Pharmacology and Therapeutics 2006; 23:1703-1711
 

Paul KS Chan, Pak Leong Lim, Esther YM Liu, Jo LK Cheung, Danny TM Leung, Joseph JY Sung. Antibody avidity maturation during severe acute respiratory syndrome-associated coronavirus infection. Journal of Infectious Diseases July 2005; 192(1):166-169