Professor David Shu Cheong HUI (許樹昌教授)
MBBS (UNSW), MD (UNSW), FRACP, FRCP (Lond., Glasg, Edin.), FHKCP, FHKAM 

Associate Director (Clinical Liaison), JC School of Public Health and Primary Care     

Director, Stanley Ho Centre for Emerging Infectious Diseases,JC School of Public Health and Primary Care

Stanley Ho Professor of Respiratory Medicine, Department of Medicine & Therapeutics

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Dr. Hui graduated from the University of New South Wales in 1985. He then trained in Respiratory and Sleep Medicine in Sydney, Australia.  Dr Hui was heavily involved in the clinical management of patients with SARS during the major outbreak in 2003. He served as a WHO advisor to review the clinical management of influenza A(H5N1)  during the early human outbreak in Vietnam in Feb 2004 and has since been a regular advisor to the WHO on the clinical management of severe acute respiratory infections. 

He has contributed to the WHO treatment guidelines (including the clinical management of influenza A (H5N1) virus in 2007, clinical management of influenza A (H1N1) pandemic in 2009, and the Middle East Respiratory Syndrome) and the WHO training workshop in the clinical management of influenza A(H7N9) and other severe acute respiratory infections in May 2014.

Dr Hui has published over 220 peer-reviewed journal articles and 23 book chapters since joining the CUHK in 1998. 

Teaching Modules
MB ChB Programme
Research Postgraduate Programme

Research interests 
  • Clinical management of emerging respiratory infections
  • The safety of respiratory therapy in the post SARS era
  • The efficacy of the medical ward airflow in preventing nosocomial infections
  • Sleep disordered breathing and common airway diseases.

Selected Publications 
  1. Hui DS, Hayden FG. Host and Viral Factors in Emergent Influenza Virus Infections. Clin Infect Dis. 2014; 58(8):1104-6.
  2. Hui DS, Memish ZA, Zumla A. Severe acute respiratory syndrome vs. the Middle East respiratory syndrome. Curr Opin Pulm Med. 2014;20(3):233-41.
  3. Hui DS, Zumla A. Advancing priority research on the Middle East respiratory syndrome coronavirus. J Infect Dis. 2014;209(2):173-6. 
  4. Liu KH, Chu WC, To KW, Ko FW, Ng SS, Ngai JC, Chan JW, Ahuja AT, Hui DS. Mesenteric fat thickness is associated with increased risk of obstructive sleep apnoea. Respirology. 2014;19(1):92-7.
  5. Hui DS, Lee N. Adjunctive therapies and immunomodulating agents for severe influenza. Influenza Other Respir Viruses. 2013;7 Suppl 3:52-9.
  6. Hui DS, Lee N, Chan PK. Adjunctive therapies and immunomodulatory agents in the management of severe influenza. Antiviral Res. 2013;98(3):410-6. 
  7. Hui DS. Tracking the transmission and evolution of MERS-CoV. Lancet. 2013;382(9909):1962-4.
  8. Lee N, Hui DS, Zuo Z, Ngai KL, Lui GC, Wo SK, Tam WW, Chan MC, Wong BC, Wong RY, Choi KW, Sin WW, Lee EL, Tomlinson B, Hayden FG, Chan PK. A Prospective Intervention Study on Higher-dose Oseltamivir Treatment in Adults Hospitalized with Influenza A and B infections. Clin Infect Dis. 2013;57(11): 1511-9.
  9. Ison MG, Hui DS, Clezy K, O'Neil BJ, Flynt A, Collis PJ, Simon TJ, Alexander WJ. A clinical trial of intravenous peramivir compared with oral oseltamivir for the treatment of seasonal influenza in hospitalized adults. Antivir Ther. 2013;18(5): 651-61.
  10. Ko FW, Leung TF, Wong GW, Chu JH, Sy HY, Hui DS. Determinants and reference equation of exhaled nitric oxide in the Chinese population. Eur Respir J. 2013; 42(3):767-775.
  11. Chan PK, Chan MC, Cheung JL, Lee N, Leung TF, Yeung AC, Wong MC, Ngai KL, Nelson EA, Hui DS. Influenza B lineage circulation and hospitalisation rate in a subtropical city, Hong Kong, 2000-2010. Clin Infect Dis. 2013;56(5):677-84.
  12. Chan MTV, Chow B, Chu Leo, Hui DS. Mask ventilation and dispersion of exhaled air. Am J Respir Crit Care Med 2013;187(7):e12-14.
  13. Hui DS, Chow BK, Chu L, Ng SS, Lee N, Gin T, Chan MT. Exhaled air dispersion during coughing with and without wearing a surgical or N95 mask. Plos One 2012; 7(12):e50845.
  14. Hui DS, Shang Q,  Ko FW,  Ng SS,  Szeto CC,  Ngai J,  Tung A,  To KW, Chan TO, Yu CM. A prospective cohort study of the long-term effects of CPAP on carotid artery intima-media thickness in Obstructive sleep apnoea syndrome. Respir Res 2012;13(1):22.
  15. Hurt AC, Chotpitayasunondh T, Cox NJ, Daniels R, Fry AM, Gubareva LV, Hayden FG, Hui DS, Hungnes O, Lackenby A, Lim W, Meijer A, Penn C, Tashiro M, Uyeki TM, Zambon M; WHO Consultation on Pandemic Influenza A (H1N1) 2009 Virus Resistance to Antivirals. Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives. Lancet Infect Dis 2012;12:240-248.
  16. Lee N, Wong CK, Chan PK, Chan MCW, Wong RY, Lun SW, Ngai KL, Lui GC, Wong BC, Lee SK, Choi KW, Hui DS. Cytokine Response Patterns in Severe Pandemic 2009 H1N1 and Seasonal Influenza among Hospitalized Adults. PloS One 2011;6(10):e26050.
  17. Lee N, Hui DS. Dexamethasone in community-acquired pneumonia. Lancet.2011; 378(9795):979-980.
  18. Lee N, Chan PK, Wong CK, Wong KT, Choi KW, Goynt GM, Lam P, Chan MC, Wong BC, Lui GC, Sin WW, Wong RY, Lam WY, Yeung AC, Leung TF, So HY, Yu AW, Sung JJ, Hui DS. Viral Clearance and Inflammatory Response Patterns in Adults Hospitalized for Pandemic 2009 Influenza A(H1N1)Virus Pneumonia. Antiviral therapy 2011;16:237-247.
  19. Lee N, Chan PK, Lui GC, Wong BC, Sin WW, Choi KW, Wong RY, Lee EL, Yeung AC, Ngai KL, Chan MC, Lai RW, Yu AW, Hui DS. Complications and Outcomes of Pandemic 2009 Influenza A (H1N1) in Hospitalized Adults – how are they Different from Seasonal Influenza? J Infect Dis 2011;203:1739-1747.
  20. Bautista E, Chotpitayasunondh T, Gao ZC, Harper SA, Hayden FG, Hui DS, Kettner JD, Kumar A, Lim M, Nicholson KG, Penn C, Shaw M, Shindo N, Uyeki TM. Clinical Aspects of Pandemic Influenza A (H1N1) 2009. N Engl J Med 2010; 362: 1708-1719. 
  21. Hui DS, Lee N, Chan PK. Clinical Management of Pandemic (H1N1) Infection. Chest 2010;137:916-925.
  22. Hui DS, Chow BK, Hall SD, Ng SS, Gin T, Sung JJ, Chan MT. Exhaled air dispersion distances during application of non-invasive ventilation via different Respironics face masks. Chest 2009;136:998-1005.
  23. Hui DS, Chow BK, Hall SD, Ng SS, Gin T, Chan MT. Exhaled air and aerosolized droplet dispersion during application of a jet nebulizer. Chest 2009; 135:648-654.
  24. Hui DS, Woo J, Hui E, Foo A, Ip M, To KW, Cheuk ES, Lam WY, Sham A, Chan PK. Influenza-like illness in residential care homes: A study of the incidence, aetiological agents, natural history, and health resource utilization. Thorax 2008; 63:690-697.