Professor Shui-shan LEE (李瑞山教授)
MBBS, MD (HK), FHKAM (Medicine), FHKCP, FHKCCM, FRCPA,
FRCP (Glasg, Edin., Lond.), FFPH 


Deputy Director, Stanley Ho Centre for Emerging Infectious Diseases; and
Professor of Infectious Diseases




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Biography 

Prof. SS Lee, MBBS, MD graduated from the Medical School of the University Hong Kong in 1982 and 1995 respectively. After graduation he underwent training in internal medicine, developed keen interest in clinical immunology and in the last decade, pursued public health research and practice. He is currently a fellow with professional institutions in internal medicine, pathology and public health: FRCP(Lond, Edin, Glasg), FRCPA, FFPH, FHKAM(medicine), FHKCP, FHKCCM.
In 1991, Dr Lee was appointed head of the newly established Department of Health Special Preventive Programme for AIDS and viral hepatitis. In 2005, he joined the Chinese University of Hong Kong as chair professor in infectious diseases, and is currently staff member of the Stanley Ho Centre for Emerging infectious Diseases and the Department of Microbiology. His research interest includes epidemiology of infectious diseases, application of GIS in public health, and interdisciplinary research on HIV/AIDS and related issues.



Teaching Commitment 
  • Undergraduate teaching in HIV prevention, HIV-related opportunistic infections, and clinical HIV management for year 3, 4 and 5 medical students (MBChB)
  • Undergraduate teaching in infectious disease for BSc in Public Health
  • Programme director for Master of Science in Applied Epidemiology
     

Coordinator of MPH (Master of Public Health) Infectious Diseases concentration, and Course Director for the following postgraduate short courses:

EID6510  Control of HIV infection
PBH7005  Infectious diseases in public health practice
PBH7206  Application of GIS in public health
PBH7207/8 Topics in microbiology and infectious diseases I/II
PBH7209 Infection control in health care and community settings
PBH7211 Surveillance and infectious disease investigations
PBH7212 Methods in infectious disease epidemiology


Research interests 
  • Epidemiology of infectious diseases, with focus on the application of spatial, social and molecular techniques
  • Clinical epidemiology of HIV/AIDS
  • Treatment optimization in HIV infection Interdisciplinary research on infection risk in heroin addiction

Selected Publications
Journal or Magazine Article

Lee SS, Tam DKP, Tan Y, Mak WL, Wong KH, Chan JHK, Yam WC. An exploratory study on the social and genotypic clustering of HIV infection in men having sex with men. AIDS 2009; 23(13):1755-1764

Huizhen Li, William Goggins, Shui Shan Lee. Multilevel analysis of HIV related risk behaviors among heroin users in a low prevalence population. BMC Public Health 2009; 9:137

Yi T, Wei QH, Chen LJ, Chan PC, Lai WS, He ML, Kung HF, Lee SS. Molecular epidemiology of HCV monoinfection and HIV/HCV coinfection in injection drug users in Liuzhou, Southern China. PLoS ONE 2008;3(10):e3608
 

Lee SS, Tam DKP. Ho RLM, Wong KH. Shift of preference of location for sexual partnership in men having sex with men (MSM) in an Asian population. Sexual Health 2008; 5(4):373-374
 

Pang PTT, Lee SS. Measuring the geographic coverage of methadone maintenance programme in Hong Kong by using geographic information system (GIS). Int J Health Geogr 2008; 7:5
 

Tam DKP, Lee SS, Lee S. Impact of SARS on avian influenza preparedness in healthcare workers. Infection 2007; 35(5):320-325
 

Lee SS. A humble service that has delivered public health good. Public Health 2007; 121:884-886
 

Lee SS, Zhang B, He ML, Chang VSC, Kung HF. Screening of active ingredients of herbal medicine for interaction with CYP4503A4. Phythother Res 2007; 21(11):1096-1099
 

Ho CF, Lee SS, Wong KH, Cheng LS, Lam MY. Setting a minimum threshold CD4 count for initiation of highly active antiretroviral therapy in HIV-infected patients. HIV Med 2007; 8:181-185
 

Lee SS, Ma K, Chu EKY, Wong KH. The phenomenon of missing dose in a cohort of HIV patients with good adherence to HAART. Int J STD AIDS 2007; 18(13):167-170
 

Li MQ, Lee SS, Gan ZG, Tan Y, Meng JH, He ML. Achieving a high coverage - the challenge of controlling HIV spread in heroin users. Harm Reduct J 2007; 4:8
 

Yu H, Jing H, Chen Z, Zheng H, Zhu X, Wang H, Wang S, Liu L, Zu R, Luo L, Xiang N, Liu H, Liu X, Shu Y, Lee SS, Chuang SK, Wang Y, Xu J, Yang W, and the Streptococcus suis study groups. Human Streptococcus susis infection outbreak, Sichuan, China. Emerg Infect Dis 2006; 12(6):914-920
 

Tong K, He ML, Lin CK, Guo L, Kung HF, Sung JJY, Lee SS. The implication of a high allelic frequency of CYP2B6 G516T in ethnic Chinese. Clin Infect Dis 2006; 43:541-542
 

Lee SS, Lee KCK, Wan WY, Wong KH. A urine-based approach to scale up HIV testing in drug users. AIDS 2006; 20(9):1349-1351

Zhao XY, Lee SS, Wong KH, Chan KCW, Ng F, Chan CCS, Han D, Yam WC, Yuen KY, Ng MH, Zheng BJ. Functional analysis of naturally occurring mutations in the open reading frame of CCR in HIV-infected Chinese patients and healthy controls. J AIDS 2005; 38:509-517
 

Zhao XY, Lee SS, Wong KH, Chan KCW, He ZM, M S, Chan CCS, Ho T, Ng MH, Zheng BJ. A novel CCR5 mutation selectively affects immunoreactivity and fusogenic property of the HIV co-receptor in a slow progressing HIV patient. AIDS 2004; 18(12):1729-1732
 

Wong KH, Liu YM, Ng PSP, Young BWY, Lee SS. Epidemiology of hepatitis A and hepatitis E infection and their determinants in adult Chinese community in Hong Kong. J Med Virology 2004; 72:538-544
 

Zheng BJ, Guan Y, Wong KH, Zhou J, Wong KL, Young BWY, Lu LW, Lee SS. SARS-related Virus Predating SARS Outbreak, Hong Kong. Emerg Infect Dis 2004; 10:176-178
 

Wong KH, Lee SS, Lim WL, Low HK. Adherence to methadone is associated with a lower level of HIV-related risk behaviours in drug users. J Substance Abuse Treatment 2003; 24:233-239
 

Young BWY, Lee SS, Lim WL, Yeoh EK. The long term efficacy of plasma-derived hepatitis B vacine in babies born to carrier mothers. J Viral Hepatitis 2003; 10(1):23-30
 

Zheng BJ, Zhao XY, Zhu NS, Chan CP, Wong KH, Chan KCW, Yam WC, Yuen KY, Lee SS. Polymorphisms of CCR5 gene in a Southern Chinese population and their effects on disease progression in HIV infection. AIDS 2002; 16(8):2480-2482
 

Ho TTY, Wong KH, Lee SS. Low yield of chest radiograph in screening for active pulmonary tuberculosis in HIV-infected patients in Hong Kong. Int J STD & AIDS 1999; 10:409-412
 

Ho TTY, Chan KCW, Wong KH, Lee SS. Indinavir-associated facial lipodystrophy in HIV infected patients. AIDS Patients Care and STDs 1999; 13:11-16
 

Wong KH, Lee SS, Chan KCW, Choi TMY. Redefining AIDS: case exemplified by Penicillium marneffei infection in HIV-infected people in Hong Kong. J STD & AIDS 1998; 9:555-556
 

Kwan LC, Ho YY, Lee SS. The declining HBsAg carriage rate in pregnant women in Hong Kong. Epidemiol Infect 1997; 119:281-283
 

Kam KM, Leung WL, Kwok MY, Hung MY, Lee SS, Mak WP. Lymphocyte subpopulation reference ranges for monitoring human immunodeficiency virus-infected Chinese adults. Clin Diagn Lab Immunol 1996; 3, 326-330
 

Lee SS, Lo YC, Young BWY, Wong KH, Lim WL. A reduced dose approach to hepatitis B vaccination for low risk newborns and preschool children. Vaccine 1995; 13(4):373-376
 

Lee SS, Li PCK, Li CS. Clinical profile of Chinese patients with systemic lupus erythematosus. Lupus 1993; 2:105-109

Lee SS, Adu D, Thompson RA. Anti-myeloperoxidase antibodies in systemic vasculitis. Clin Exp Immunol 1990; 79:41-46


Book Article or Chapter

SS Lee, Justin Wu, KH Wong (eds). HIV Manual 2007. Stanley Ho Centre for Emerging Infectious Diseases and Centre for Health protection, 2007
 

Wong NS , Law CY, Lee MK, Lee SS, Lin H. An alert system for informing environmental risk for dengue infection. In: Lai, P.C. and Mak, SH. (eds) GIS for Health and the Environment: Development in the Asia Pacific Regions(pp 173-183). Berlin: Springer Verlag, 2007
 

Pang PTT, Lee P, Leung WY, Lee SS, Lin H. A "spatiaotemporal analysis of heroin addiction" system for Hong Kong. In: Lai PC and Mak SH. (eds) GIS for Health and the Environment: Development in the Asia Pacific Regions (pp 229-242). Berlin: Springer-Verlag, 2007
 

Lee SS, Lee KCK, Wan WY, Wong KH. Incorporation of a regularized urine-based HIV testing in methadone maintenance treatment programme for enhancing the effectiveness of HIV prevention in drug users. In: New Topics in Substance Abuse Treatment (pp. 171-190). Louise A Bennett (ed). New York: Nova Science Publishers, Inc., 2006
 

Saw TA, Lo KK, Lee SS, Chong LY. Prevention care and control of STD in Hong Kong. In: Sexually Transmitted Diseases in Asia and the Pacific. Brown T, Chan R, Mugrditchian D, Mulhall B, Plummer D, Sittitrai W, eds. Australia: Venereology Publishing Inc, 1998
 

Lee SS. Implication of antenatal HIV screening. In: Neonatal and perinatal screening - the Asian Pacific perspective (pp37-39). Lam S T S 7 Pang C C P. (eds). Hong Kong: Chinese University Press, 1997