Professor Benjamin Hon Kei YIP (葉漢基教授)                                                                                                                                                                                                                    
BRBS, MS (Swe), PhD (Karolinska Inst, Swe)

Research Assistant Professor                                            
                                                                   
                                                                                                         
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Biography 

Professor Yip obtained his PhD in biostatistics from the department of medical epidemiology and biostatistics, Karolinska Institutet, Sweden, in 2008. His thesis focused on statistical method development to estimate the relative contributions of genetic and environmental factors on the concurrence for diseases – by using national-based family registries.  After his PhD, he worked as a post doc fellow at the Psychiatry department of the University of Hong Kong. Professor Benjamin Yip joined the School of Public Health and Primary Care as a Research Assistant Professor at the Division of Family Medicine and Primary Health Care in September 2011. 
His research interests include statistical methodology and application in psychosis, genetic and environment determination on human diseases, disease comorbidity and survival analysis.     

Teaching 
  • PBHT6900 - Planning statistical methods and power calculation, Statistical Consultation 
Research Interest 
  • Statistical method development for epidemiological studies
  • Genetic and Environmental interaction
  • Genetic epidemiology
  • Psychiatry
  • Comorbidity analysis
  • Register-based statistical analysis
Publications 

Ngan ES, Garcia-Barceló MM, Yip BH, Poon HC, et al., “Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans.”J Clin Invest. 2011 Aug [Epub ahead of print]

Yip BH, Moger T, Pawitan Y. “Genetic analysis of age-at-onset traits based on case-control family data”. Stat in Med 29:3258-66, 2010.

So HC, Yip BH, Sham PC. “Estimating the total number of susceptibility variants underlying complex disease from genome-wide association studies”. Plos One Nov [Epub ahead of print], 2010

Moger TA, Haugen M, Yip BH, Gjessing HK and Borgan O. “A hierarchical frailty model applied to two-generation melanoma data.” Lifetime Data Anal Nov 2010 [Epub]

Garcia-Barceló MM, Miao X, Tang CS, So HC, Tang W, Leon TY, So M, Yip B et al. “No NRG1 V266L in Chinese patients with schizophrenia. Psychiatr Genet. Oct 25. [Epub ahead of print], 2010.
 
Tang CS, Sribudiani Y, Miao XP, de Vries AR, Burzynski G, So MT, Leon YY, Yip BH, Osinga J, Hui KJ, Verheij JB, Cherny SS, Tam PK, Sham PC, Hofstra RM, Garcia-Barceló MM. “Fine mapping of the 9q31 Hirschsprung's disease locus.” Hum Genet. 127(6):675-83. 2010.

Leung M, Cheung C, Yu K, Yip B, Sham P, Li Q, Chua S, McAlonan G. “Gray matter in First-Episode Schizophrenia before and after antipsychotic drug treatment. Anatomical Likelihood estimation meta-analysis with sample size weighting.” Schizophr Bull. Sept [Epub] 2009.

Lichtenstein P, Yip BH, Björk C, Pawitan Y, Cannon TD, Sullivan PF, Hultman CM. “Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study”. Lancet 17:234-9, 2009

Yip BH, Reilly M, Cnattinguis S, Pawitan Y. “Matched ascertainment of informative for complex genetic modelling“. Behav Genet 40:404-14, 2009.

Yip BH, Björk C, Lichtenstein P, Pawitan P, Hultman CM. “Covariance model for multivariate binary traits in family data analysis”. Stat Med 30:1086-105, 2008.

Mok BW, Ribacke U, Winter G, Yip BH, Tan CS, et al. “Comparative transcriptomal analysis of isogenic Plasmodium falciparum clones of distinct antigentic and adhesive phenotypes”. Mol Biochem Parasitol 151:184-92, 2007.

Lindström L, Yip B, Lichtenstein P, Pawitan Y, Czene K. “Etiology of familial aggregation in melanoma and squamous cell carcinoma of the skin”. Cancer Epidemiol Biomarkers Prev 16:1639-43, 2007.

Noh M, Yip B, Lee Y, Pawitan Y. “Multicomponent variance estimation for binary traits in family-based studies”. Genet Epidemiol 30:37-47, 2006

Yip BH, Pawitan Y, Czene K. “Parental age and risk of childhood cancers: a population-based cohort study from Sweden”. Int J Epidemiol, 35:1495-503, 2006

 
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