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Dr. Denise Pui-chung CHAN (陳珮琮博士)

 

Research Fellow

JC School of Public Health and Primary Care
 

Email: denisechan@cuhk.edu.hk

Division

Division of Infectious Diseases

Biography

Dr. Denise Chan is a Research Fellow at the Division of Infectious Diseases who has a special interest in antimicrobial resistance (surveillance, clinical and molecular epidemiology) and viral infections. Her research focuses on the detection, identification, and therapeutic monitoring of infectious diseases. Studies are directed toward understanding the mechanisms of drug resistance and transmission dynamics of viral infections.

Research Interest

  • Infectious diseases

  • Molecular microbiology

  • Antimicrobial resistance

  • Bioinformatics

 

Selected Publications 

  1. Yew WW, Chan DP*, Leung CC, Zhang Y, Wang R, Ng P, Lee SM. Can toxicities induced by antituberculosis drugs be better managed in diabetic patients? Eur Respir J 2017 (in press)

  2. Yew WW, Liang DC, Chan DP, Shi W, Zhang Y. Molecular mechanisms of clofazimine resistance in Mycobacterium tuberculosis. J Antimicrob Chemother 2017 (in press)

  3. Chan DP, Sun HY, Wong HT, Lee SS, Hung CC. Sexually acquired hepatitis C virus infection: a review. Int J Infect Dis 2016;49:47-58.

  4. Li S, Chan JY, Li Y, Bardelang D, Zheng J, Yew WW, Chan DP, Lee SM, Wang R. Complexation of clofazimine by macrocyclic cucurbit[7]uril reduced its cardiotoxicity without affecting the antimycobacterial efficacy. Org Biomol Chem 2016;14(31):7563-9.

  5. Wong NS, Wong KH, Lee MP, Tsang OT, Chan DP, Lee SS. Estimation of the undiagnosed intervals of HIV-infected individuals by a modified back-calculation method for reconstructing the epidemic curves. PLoS One 2016;11(7):e0159021.

  6. Chan DP, Lee MP, Wong NS, Leung RK, Naftalin CM, Lee SS. Association of immune recovery with hyperlipidaemia and apolipoprotein gene polymorphisms following highly active antiretroviral therapy in a cohort of Chinese HIV patients. BMJ Open 2016;6(4):e010998.

  7. Chan DP, Lin AW, Wong KH, Wong NS, Lee SS. Diverse origins of hepatitis C virus in HIV co-infected men who have sex with men in Hong Kong. Virol J 2015;12:120.

  8. Lam TN, Hui KH, Chan DP, Lee SS. Genotype-guided dose adjustment for the use of efavirenz in HIV treatment. J Infect 2015;71(5):607-9.

  9. Wong HT, Lee KC, Chan DP*. Community-based STI screening and increased detection of pharyngeal and urogenital Chlamydia trachomatis and Neisseria gonorrhoeae infections in female sex workers in Hong Kong. Sex Transm Dis 2015;42(4):185-91.

  10. Naftalin CM, Wong NS, Chan DP, Wong KH, Reidpath DD, Lee SS. Three different patterns of CD4 recovery in a cohort of Chinese HIV patients following antiretroviral therapy - a five-year observational study. Int J STD AIDS 2015;26(11):803-9.

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