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Dr. Denise Pui-chung CHAN (陳珮琮博士)


Research Fellow

JC School of Public Health and Primary Care



Division of Infectious Diseases


Dr. Denise Chan is a Research Fellow at the Division of Infectious Diseases who has a special interest in antimicrobial resistance (surveillance, clinical and molecular epidemiology) and viral infections. Her research focuses on the detection, identification, and therapeutic monitoring of infectious diseases. Studies are directed toward understanding the mechanisms of drug resistance and transmission dynamics of viral infections.

Research Interest

  • Infectious diseases

  • Molecular microbiology

  • Antimicrobial resistance

  • Bioinformatics


Selected Publications 

  1. Yew WW, Leung CC, Chang KC, Zhang Y, Chan DP. Can treatment outcomes of latent TB infection and TB in silicosis be improved? J Thorac Dis 2019;11: E8-E10.

  2. Yew WW, Chang KC, Chan DP, Zhang Y. Can modulating redox status help to enhance antituberculosis drug efficacy? Tuberculosis (Edinb) 2018;(113):177-8.

  3. Yew WW, Chang KC, Leung CC, Chan DP*, Zhang Y. Vitamin C and Mycobacterium tuberculosis persisters. Antimicrob Agents Chemother 2018;62(11); e01641-18.

  4. To KW, Kam KM, Chan DP, Yip WH, Chan KP, Lo R, Ng S, Ngai J, Lee SS. Utility of GeneXpert in analysis of bronchoalveolar lavage samples from patients with suspected tuberculosis in an intermediate-burden setting. J Infect 2018;77(4):296-301.

  5. Yew WW, Chang KC, Chan DP. Oxidative stress and first-line antituberculosis drug-induced hepatotoxicity. Antimicrob Agents Chemother 2018;62(8):e02637-17.

  6. Yew WW, Yoshiyama T, Leung CC, Chan DP. Epidemiological, clinical and mechanistic perspectives of tuberculosis in older people. Respirology 2018;23(6):567-575.

  7. Wong NS, Lee CK, Ng SC, Wong HK, Chan DP, Lee SS. Prevalence of hepatitis C infection and its associated factors in healthy adults without identifiable route of transmission. J Viral Hepat 2018;25(2):161-170.

  8. Yew WW, Chan DP, Leung CC, Zhang Y. RE: "Dietary intake of antioxidant vitamins and carotenoids and risk of development active tuberculosis in a prospective population-based cohort" Am J Epidemiol 2018;287(7):1570-1571.

  9. Yew WW, Chan DP, Singhal, Zhang Y, Lee SS. Does oxidative stress contribute to adverse outcomes in HIV-associated TB? J Antimicrob Chemother 2018;73(5):1117-1120.

  10. Yew WW, Liang DC, Chan DP, Shi W, Zhang Y. Molecular mechanisms of clofazimine resistance in Mycobacterium tuberculosis. J Antimicrob Chemother 2017; 72(10):2943-2944.

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