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Professor Paul Kay-sheung CHAN (陳基湘教授)

MBBS (HK), MSc, MD (CUHK), FRCPath, FHKCPath, FHKAM (Pathology)  

Deputy Director, Stanley Ho Centre for Emerging Infectious Diseases

JC School of Public Health and Primary Care

Professor (Clinical)



Personal Website:


Division of Infectious Diseases


Professor Paul Chan is Clinical Professor and Chairman of the Department of Microbiology, and Deputy Director of the Stanley Ho Centre for Emerging Infectious Diseases, Faculty of Medicine, The Chinese University of Hong Kong. He is also Honorary Consultant in Microbiology for the New Territories East Cluster Hospitals of Hong Kong Hospital Authority. Professor Chan is a renowned clinical virologist with special interest in tumour virology, human respiratory viruses and microbiome. He serves many key professional bodies in Hong Kong, including the Scientific Committee on Emerging and Zoonotic Diseases of the Centre for Health Protection, the Grant Review Board for Medical and Health Research Fund, the Hong Kong College of Pathologists Examiner Committee. Professor Chan is also a partner of the Global Outbreak Alert and Response Network He is Editor-in-Chief of the Journal of Virological Methods. Professor Chan has published 14 book chapters and more than 350 scientific papers, and attained an H-index of 53.

Research Interest

  • Clinical management of emerging respiratory infections

  • The safety of respiratory therapy in the post SARS era

  • The efficacy of the medical ward airflow in preventing nosocomial infections

  • Sleep disordered breathing and common airway diseases


Selected Publications 

  1. He L, Law PTY, Wong CK, Chan JCN, Chan PKS. Exendin-4 Exhibits Enhanced Anti-tumor Effects in Diabetic Mice. Scientic Reports. 2017; 7: 1791.

  2. Lam EW, Chan JY, Chan AB, Ng CS, Lo ST, Lam VS, Chan MM, Ngai CM, Vlantis AC, Ma RK, Chan PKS. Prevalence, Clinicopathological Characteristics, and Outcome of Human Papillomavirus-Associated Oropharyngeal Cancer in Southern Chinese Patients. Cancer Epidemiology, Biomarkers and Prevention. 2016; 25: 165-73.

  3. Chan MC, Lee N, Hung TN, Kwok K, Cheung K, Tin EK, Lai RW, Nelson EA, Leung TF, Chan PKS. Rapid emergence and predominance of a broadly recognizing and fast-evolving norovirus GII.17 variant in late 2014. Nature Communications 2015; 6: 10061.

  4. Chan PKS, Tam WW, Lee TC, Hon KL, Lee N, Chan MC, Mok HY, Wong MC, Leung TF, Lai RW, Yeung AC, Ho WC, Nelson EA, Hui DS. Hospitalization Incidence, Mortality, and Seasonality of Common Respiratory Viruses Over a Period of 15 Years in a Developed Subtropical City. Medicine (Baltimore) 2015; 94: e2024.

  5. Lee N, Chan MC, Lui GC, Li R, Wong RY, Yung IM, Cheung CS, Chan EC, Hui DS, Chan PKS. High Viral Load and Respiratory Failure in Adults Hospitalized for Respiratory Syncytial Virus Infections. Journal of Infectious Diseases 2015; 212: 1237-1240.

  6. Chan MC, Leung TF, Kwok AK, Lee N, Chan PKS. Characteristics of patients infected with norovirus GII.4 Sydney 2012, Hong Kong, China. Emerging Infectious Diseases 2014; 20: 658-661.

  7. Zhang C, Park JS, Grce M, Hibbitts S, Palefsky JM, Konno R, Smith-McCune KK, Giovannelli L, Chu TY, Picconi MA, Piña-Sánchez P, Settheetham-Ishida W, Coutlée F, De Marco F, Woo YL, Ho WC, Wong MC, Chirenje MZ, Magure T, Moscicki AB, Sabol I, Fiander AN, Chen Z, Chan MC, Cheung TH, Burk RD, Chan PKS. Geographical distribution and risk association of human papillomavirus genotype 52-variant lineages. Journal of Infectious Diseases 2014; 210: 1600-1604.

  8. Chan PKS, Chan MC, Cheung JL, Lee N, Leung TF, Yeung AC, Wong MC, Ngai KL, Nelson EA, Hui DS. Influenza B lineage circulation and hospitalisation rate in a subtropical city, Hong Kong, 2000-2010. Clinical Infectious Diseases 2013; 56: 677-684.

  9. Lee N, Lui GC, Wong KT, Li TC, Tse EC, Chan JY, Yu J, Wong SS, Choi KW, Wong RY, Ngai KL, Hui DS, Chan PKS. High morbidity and mortality in adults hospitalized for respiratory syncytial virus infections. Clinical Infectious Diseases 2013; 57: 1069-1077.

  10. Lee N, Hui DS, Zuo Z, Ngai KL, Lui GC, Wo SK, Tam WW, Chan MC, Wong BC, Wong RY, Choi KW, Sin WW, Lee EL, Tomlinson B, Hayden FG, Chan PKS. A Prospective Intervention Study on Higher-Dose Oseltamivir Treatment in Adults Hospitalized With Influenza A and B Infections. Clinical Infectious Diseases 2013; 57: 1511-1519.

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