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學院教職員

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個人簡介

葉漢基教授於2011年加入香港中文大學公共衞生與基層醫療學院,現為助理教授。 2008年,他在瑞典卡羅林斯卡學院獲得博士學位。 他的論文是開發估計家譜數據中疾病傾向性和相關性的方差分量的隨機效應模型的統計方法。 葉教授與他的博士生導師Yudi Pawitan教授一起,在一個大規模的人口樣本中研究了精神分裂症和雙相情感疾病之間的共病性和傾向性。 這項研究結束了精神病學中最持久的爭論之一,即精神分裂症和躁鬱症是完全不同還是與相同病因過程的臨床實現(Lancet 2009)。 他繼續發展和完善這些方法,體現在最近國際頂級同行評審稿件中發表的文章(JAMA Psychiatry 2019 ,Biological Psychiatry 2018,2020)。

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在卡羅林斯卡學院繼續從事遺傳流行病學研究的同時,葉教授還擔任多項臨床研究的首席統計學家,包括臨床試驗和佇列研究,家庭健康賬戶指導委員會成員,服務學習委員會成員(崇基學院),以及世界大學多發病綜合護理模式工作小組的主要成員。 他正在教授衞生經濟學的本科和研究生課程。 目前,他正在指導4名博士生。 在此之前,他曾指導/共同指導其他四名已畢業的博士生。

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葉教授是許多資助專案的主要研究者或首席生物統計學家(見下文)。 他有83篇學術文章(更新於20/07/2020), h指數為17。 完整的論文清單請見 :

https://www.ncbi.nlm.nih.gov/myncbi/1Jiy6rs2e8zkdf/bibliography/public/

研究方向

  • 心理健康:自閉症譜系障礙的流行病學和遺傳流行病學

  • 電子健康:可穿戴性、監測、行為

  • 衞生經濟學:基於試驗的經濟評估

近期獲資助研究項目

  • As Principal Investigator or Co-Principal Investigator

    • Sex Differences in Autism Spectrum Disorder: A Population-based Genetic Epidemiological Study. (ECS24108520, 2020)

    • The Hong Kong Mental Morbidity Survey for Older People – HKMMSOP (FHB, 2019-2022)

    • Post-discharge health care utilization and needs among young stroke patients: a prospective cohort study (CUHK Direct Grant 143386979, 2020-2021)

    • Integrating Health & Social Care Services to Tackle Asia’s Ageing Population & Rise in Chronic & Multi- Morbidity: Global Developments & Lessons (WUN RDF 4930631, 2020 – 2021)

 

  • As Co-Investigator

    • Effectiveness of a Complex Exercise Intervention to Normalize Blood Pressure and Its Nocturnal Dipping in Patients with Hypertension in Primary Care: A Randomized-controlled Trial (Co-I, HMRF136636363, 2020-2023)

    • Novel Retinal Imaging Biomarkers for Children Amblyopia (Co-I, HMRF136635437, 2020-2023)

    • Preventing Curve Progression and the Need for Bracing in Early Diagnosed Adolescent Idiopathic Scoliosis Using Calcium Plus Vitamin D Supplementation – A Randomized Double-blinded Placebo-controlled Trial (Co-I, GRF138172334, 2018-2023)

    • Low-Concentration Atropine for Myopia Progression (LAMP) Phase 4 Study: 5-year follow up to evaluate the optimal treatment regimen and long-term efficacy of low-concentration atropine eye drops (GRF138277701, 2020-2022)

    • Incidence, Clinical Presentation, Treatment Modalities, and Long Term Outcomes of Retinoblastoma in Hong Kong: Hong Kong Retinoblastoma Registry (HMRF136630353, 2020-2022)

    • Tender for the Provision of Services of the Monitoring and Evaluation Study of Kwai Tsing District Health Centre (FHB136603387, 2019-2022)

    • Combining Mind-body Physical Exercise, Cognitive Training, and Nurse-led Risk Factor Modification to Enhance Cognition among Older Adults with Mild Cognitive Impairment: A Randomized Controlled Trial (HMRF136562162, 2019-2022)

    • Complex Interventions for Reducing 30-day Avoidable Hospital Readmission among Adults: Recommendations for Hong Kong via Overview of Systematic Reviews and Stakeholder Consensus (HMRF136561236, 2019-2022)

    • Vibration Therapy as a Primary Prevention Strategy of Fragility Fracture, a Local Invention for the Local Community (Research Committee Group Research Scheme CUHK 136553354, 2020-2021)

    • Do Women with a History of Recurrent Miscarriage Have a Higher Risk of Obstetric and Perinatal Complications in a Subsequent Pregnancy? A Cohort Study (HMRF136594341, 2020-2021)

    • The Feasibility and Effects of Mindfulness Based Relapse Prevention (MBRP) on Reducing Craving and Addictive Behaviour in Local Adults with Substance Abuse Disorders (Beat Drugs Fund 136611718, 2019-2021)

    • Exposure to Alcohol Social Media Marketing and Associations with Young Adult''s Drinking Expectancies and Behaviours: A Study to Inform Regulation and Health Promotion (HMRF136628500, 2020-2021)

    • The Effect of Virtual Reality Phacoemulsification Cataract Extraction Simulation Surgery Training on Patient Safety and Outcomes: A Randomised Controlled Trial (VRPhaco Sim Study) (HMRF136434203, 2018-2021)

    • The effects of a mindfulness based intervention - MYmind - for children with ADHD and their parents: a randomised controlled trial (HMRF 138201888, 2018-2020)

    • Building Capacity to Promote Winter Health in Elderly: Co-production of a Volunteer-based Home Care Programme for Post-discharged Elderlies by Medical-social-academic Sector (HCPS 136453631, 2018-2020)

    • Harms and Second-hand Harms of Alcohol Consumption in Hong Kong: A Population-based Study to Inform Public Policy (HMRF136572358, 2019-2020)

    • Feasibility and Acceptability of World Health Organization’s “Best Buys” for Reducing the Harms of Alcohol Use in Hong Kong: Comparison of Population Attitudes and Stakeholder''s Opinions. (GRF 138207457, 2017-2020)

部份學術文章

  1. Bai D, Marrus N, Yip BHK, Reichenberg A, Constantino JN, Sandin S. Inherited Risk for Autism Through Maternal and Paternal Lineage. Biol Psychiatry. 2020 Apr 2:S0006-3223(20)31384-6. doi:10.1016/j.biopsych.2020.03.013.

  2. Bai D, Yip BHK, Windham GC, Sourander A, Francis R, Yoffe R, Glasson E, Mahjani B, Suominen A, Leonard H, Gissler M, Buxbaum JD, Wong K, Schendel D, Kodesh A, Breshnahan M, Levine SZ, Parner ET, Hansen SN, Hultman C, Reichenberg A, Sandin S. Association of Genetic and Environmental Factors With Autism in a 5-Country Cohort. JAMA Psychiatry. 2019 Jul 17;. doi: 10.1001/jamapsychiatry.2019.1411.

  3. Yip BHK*, Bai D, Mahjani B, Klei L, Pawitan Y, Hultman CM, Grice DE, Roeder K, Buxbaum JD, Devlin B, Reichenberg A, Sandin S. Heritable Variation, With Little or No Maternal Effect , Accounts for Recurrence Risk to Autism Spectrum Disorder in Sweden. Biological Psychiatry. 2018;83:589–97.

  4. Yip BHK*, Leonard H, Stock S, Stoltenberg C, Francis RW, Gissler M, Gross R, Schendel D, Sandin S. Caesarean section and risk of autism across gestational age: a multi-national cohort study of 5 million births. International Journal of Epidemiology. 2017;46:429-439.

  5. Lichtenstein P, Yip BH, Björk C, Pawitan Y, Cannon TD, Sullivan PF, Hultman CM. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. The Lancet. 2009;373:234-9.

  6. Yip BH, Pawitan Y, Czene K. Parental age and risk of childhood cancers: A population-based cohort study from Sweden. International Journal of Epidemiology. 2006;35:1495-503

Last Updated: 22 July 2020

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