學院教職員

​教學人員

王海天教授

Prof. Maggie Haitian WANG

BSc (HKUST), PhD (HKUST) 

助理教授

學術委任

  • 香港中文大學流行病學及生物統計學碩士課程聯席負責人

  • 《人類遺傳學》審稿編輯

個人簡介

王海天教授畢業於香港科技大學,獲物理學學士(榮譽)及統計學博士學位。她於2011年加入中大,擔任研究助理教授,後於2015年擔任助理教授。王教授曾於2010年和2016年分別在哥倫比亞大學和斯坦福大學做訪問學者。王博士是GRF、NSFC和HMRF基金的首席研究員。王教授是《人類遺傳學》雜誌的審稿編輯,以及國際遺傳流行病學會科學專案和交流委員會的成員。

研究方向

王海天博士的研究重點是統計遺傳學和生物資訊學,主要有傳染病基因組和人類基因組解讀兩大應用領域。在人類基因組方面,王教授的課題組開發了新的統計方法和工具,用於識別疾病易感生物標誌物,提高疾病預測準確率。在流感基因組研究方面,王教授課題組提出了連通遺傳學和流行病學的新方法,捕捉病毒突變模式,實現疫苗抗原優化。。

近期獲資助研究項目

  • PI, Health and Medical Research Fund (HMRF) commissioned research on the Novel Coronavirus Diseases (COVID-19): Characterizing whole genome stability of the novel coronavirus SARS-CoV-2. PI: Maggie Wang, 2020/04/01 – 2023/03/31

  • PI of sub-project, Health and Medical Research Fund (HMRF) 2018/19, Sub-project title: Real-time surveillance of influenza viral evolution and antigenic mutation estimation, 01/09/2019 – 31/08/2022

  • PI, National Natural Science Foundation of China (NSFC) – General Project, Improving prediction accuracy of Alzheimer's Disease by Incorporating a novel feature selection method, 01/01/2019/ - 31/12/2022

  • PI, National Natural Science Foundation of China (NSFC) – General Project, Tracking pattern of amino acids underlying seasonal influenza, 01/01/2015 – 31/12/2018

部份學術文章

  1. Xiaoxuan Xia, William K.K. Wu, Sunny H. Wong, Dabin Liu, Thomas N.Y. Kwong, Geicho Nakatsu, Pearlly S. Yan, Yu-Ming Chuang, Michael W.Y. Chan, Olabisi O. Coker, Zigui Chen, Yun K. Yeoh, Liuyang Zhao, Xiansong Wang, Wing Y. Cheng, Matthew T.V. Chan, Paul K.S. Chan, Joseph J.Y. Sung, Maggie H Wang*, Jun Yu* (2020) (co-corresponding author) Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer. Microbiome. IF=10.465, Rank 7/149 in Microbiology

  2. Chan MC, Wang MH, Chen Z, Hui DS, Kwok AK, Yeung AC, Liu KM, Yeoh YK, Lee N, Chan PK. Frequent Genetic Mismatch between Vaccine Strains and Circulating Seasonal Influenza Viruses, Hong Kong, China, 1996–2012. Emerging infectious diseases. (2018) Oct;24(10):1825. IF = 8.22. Rank 3/84

  3. Maggie Haitian Wang*, Haoyi Weng+, Rui Sun, Jack Lee, William Ka Kei Wu, Ka Chun Chong, Benny Chung-Ying Zee (2017) A Zoom-Focus Algorithm (ZFA) to locate the optimal testing region for rare variant association tests. Bioinformatics, IF=7.2. Corresponding author

  4. Maggie Haitian Wang, Rui Sun, Junfeng Guo, Haoyi Weng, Jack Lee, Inchi Hu, Pak Sham and Benny Chung-Ying Zee (2016). A fast and powerful W-test for pairwise epistasis testing. Nucleic Acids Research. IF=11.6.

  5. Rui Sun, Haoyi Weng, Inchi Hu, Junfeng Guo, William K.K. Wu, Benny Chung-Ying Zee, Maggie Haitian Wang* (2016) A W-test collapsing method for rare variant association testing in exome sequencing data. Genetic Epidemiology. DOI: 10.1002/gepi.22000.

  6. Maggie Haitian Wang*, Billy Chang, Rui Sun, Inchi Hu, Marc Ka Chun Chong, Benny Chung Ying Zee (2017), A Stratified Polygenic Risk Prediction Model with Application on CAGI Bipolar Disorder Sequencing Data. Human Mutation. 2017 Sep;38(9):1235-9. Rank 24/171 in Genetics & Heredity Science. IF=5.359. https://doi.org/10.1002/humu.23229

  7. Maggie Haitian Wang*, Heather Cordell, Kristel Van Steen (2019) Statistical Methods for Genome-wide Association Studies. Seminars in Cancer Biology. 2019 April. Rank 13/223 in Oncology. IF = 10.198 Doi: 10.1016/j.semcancer.2018.04.008

  8. Xiaoxuan Xia, Haoyi Weng, Rui Sun, Ka Chun Chong, Benny Chung Ying Zee*, Maggie Haitian Wang* Incorporating methylation genome information improves prediction accuracy for drug treatment responses. BMC Genetics. 2018 Sep;19(1):78. IF = 2.569 Doi: 10.1186/s12863-018-0644-5 (supervisor of the first author)

  9. Maggie Haitian Wang+, Ka Chun Chong+, Hau Yin Chung, Malina Storer, John Pickering, Zoltan Endre, Steven Lau, Chloe Kwok, Maria Lai, Benny Zee (2016). Use of a Least Absolute Shrinkage and Selection Operator (LASSO) Model to Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) Analysis of Exhaled Breath to Predict the Efficacy of Dialysis. Journal of Breath Research 10 (2016) 046004.

  10. Maggie Haitian Wang, Shaw-Hwa Lo, Tian Zheng and Inchi Hu (2012) A Classification Method Incorporating Interactions among Variables for High-dimensional Data. Bioinformatics (2012) 28 (21): 2834-2842

Last Updated: 22 July 2020

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