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​Prof. Regina Wing-Shan SIT 薛詠珊教授

Prof. Regina Wing-Shan SIT


MD (CUHK), MBBS (HK), DCH (HK), DPD (Cardiff), PDip Community Geriatrics (HK), DipMed (CUHK), FRACGP, FHKCFP, FHKAM (Family Medicine)

Associate Professor (Clinical)


Dr. Regina Sit is the Associate Professor (Clinical) of the Jockey Club School of Public Health and Primary Care, the Chinese University of Hong Kong. She obtained her MBBS degree from the University of Hong Kong and became a Family Medicine Specialist since 2011. In addition to her specialist training, she develops her special skills in pain management and is a Certified Interventional Pain Sonologist by the World Institute of Pain. Regina obtained her Doctor of Medicine research degree in 2020. Regina is a clinician-scientist with her clinical and research work focus on chronic musculoskeletal pain in primary care. She has a strong publication track records and her studies have been published in top-tier Primary care journals, Pain journals and Orthopaedic journals, such as Annals of Family Medicine, British Journal of General Practice, Pain, and Osteoarthritis and Cartilage. Her contributions to osteoarthritis research resulted in appointment to the Lancet Commissioner on Osteoarthritis in August 2020 as a content expert speaking for primary care physicians in the Asia region. Currently, she is the Director of the “CUHK-Jockey Club Confront Pain with Ease Project” and is leading an interdisciplinary team for chronic pain management in primary care.

Research Interests

  • Musculoskeletal Pain Medicine

Selected Publications

  1. Sit RWS,* Metformin as a potential disease-modifying agent in osteoarthritis: the present and the future. Osteoarthritis Cartilage. 2022

  2. Mengting Zhu; Dong Dong; Hermione Hin-man Lo; Samuel Yeung-shan Wong; Phoenix Kit-han Mo; *Regina Wing Shan Sit. Patient preferences in the treatment of chronic musculoskeletal pain: A systematic review of discrete choice experiments. PAIN, 10.1097, 2022

  3. Lai FTT, Yip BHK, Hunter DJ, Rabago DP, Mallen CD, Yeoh E-K, Wong SYS, Sit RWS*. Metformin use and the risk of total knee replacement among diabetic patients: a propensity-score-matched retrospective cohort study. Scientific Reports 2022;12(1):11571.

  4. Sit, Regina Wing-Shan*, Kenneth Dean Reeves, Claire Chenwen Zhong, Charlene Hoi Lam Wong, Bo Wang, Vincent Chi-ho Chung, Samuel Yeung-shan Wong, and David Rabago. "Efficacy of Hypertonic Dextrose Injection (Prolotherapy) in Temporomandibular Joint Dysfunction: A Systematic Review and Meta-Analysis." Scientific Reports 11, no. 1 (2021/07/19 2021): 14638.

  5. Sit, Regina Wing Shan, Shirley Yue Kwan Choi, Bo Wang, Dicken Cheong Chun Chan, Dexing Zhang, Benjamin Hon Kei Yip, and Samuel Yeung Shan Wong. "Neuromuscular Exercise for Chronic Musculoskeletal Pain in Older People: A Randomised Controlled Trial in Primary Care in Hong Kong." British Journal of General Practice 71, no. 704 (2021): e226-e236.

  6. Sit RWS, Yip BHK, Wang B, Chan DCC, Zhang D, Wong SYS. Chronic musculoskeletal pain prospectively predicts insomnia in older people, not moderated by age, gender or co-morbid illnesses. Scientific reports. 2021;11(1):1-7. (IF 3.998, rank 17/71 in Multidisciplinary Science 17/71, JCR 2019)

  7. Regina Sit WS*, Ricky Wu WK, D Rabago, Kenneth D Reeves, Dicken Chan CC, Benjamin Yip HK, Vincent Chung CH, Samuel Wong YS. Efficacy of Intra-Articular Hypertonic Dextrose (Prolotherapy) for Knee Osteoarthritis: A Randomized Controlled Trial. The Annals of Family Medicine 2020;18(3):235-242.

  8. Sit RWS*, Zhang D, Wang B, Wong C, Yip BHK, Woo J, Wong SYS. Sarcopenia and Chronic Musculoskeletal Pain in 729 Community-Dwelling Chinese Older Adults With Multimorbidity. J Am Med Dir Assoc. 2019;20: 1349-50

  9. Sit RWS*, Wu RWK, Law SW, Zhang DD, Yip BHK, Ip AKK, Rabago D, Reeves KD, Wong SYS. Intra-articular and extra-articular platelet-rich plasma injections for knee osteoarthritis: A 26-week, single-arm, pilot feasibility study. The Knee. 2019;26: 1032-40. (IF 1.76, rank 42/76 at Orthopedic, JCR 2019)

  10. Sit RWS, Chan KKW, Zou D, Chan DCC, Yip BHK, Zhang DD, Chan YH, Chung VCH, Reeves KD, Wong SYS. Clinic-Based Patellar Mobilization Therapy for Knee Osteoarthritis: A Randomized Clinical Trial. Annals of family medicine. 2018; 16: 521-529.

Last Updated:  15 February  2023

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