Our People

Academic Staff

Prof. Maggie Haitian WANG

王海天教授

BSc (HKUST), PhD (HKUST) 

Assistant Professor

Academic Appointments

  • Co-Director, Master of Science Program in Epidemiology and Biostatistics, CUHK

  • Review Editor, Human Genetics

Biography

Dr. Maggie Wang received her bachelor degree (Hon) in Physics, and PhD degree in Statistics from the Hong Kong University of Science and Technology (HKUST). She joint CUHK in 2011 as a Research Assistant Professor, and later Assistant Professor in 2015. Dr. Wang was a visiting scholar in Columbia University in 2010 and Stanford University in 2016. Dr. Wang is the principal investigator of GRF, NSFC, and HMRF grants. She serves as the Review Editor of Human Genetics, and in Scientific program and communication committee of the International Genetic Epidemiology Society.

Research Interests

Dr. Maggie Wang’s research focus is statistical genetics and bioinformatics with two major areas of application, infectious disease genome and human genome interpretation. In human genome, Wang’s group develops novel statistical methods and tools to identify disease susceptible biomarkers and to improve disease prediction accuracy. In influenza genome research, Wang’s group proposed new methods to bridge genetics and epidemiology and capture viral mutation pattern towards vaccine antigen optimization.

Recent Funded Research Projects 

  • PI, Health and Medical Research Fund (HMRF) commissioned research on the Novel Coronavirus Diseases (COVID-19): Characterizing whole genome stability of the novel coronavirus SARS-CoV-2. PI: Maggie Wang, 2020/04/01 – 2023/03/31

  • PI of sub-project, Health and Medical Research Fund (HMRF) 2018/19, Sub-project title: Real-time surveillance of influenza viral evolution and antigenic mutation estimation, 01/09/2019 – 31/08/2022

  • PI, National Natural Science Foundation of China (NSFC) – General Project, Improving prediction accuracy of Alzheimer's Disease by Incorporating a novel feature selection method, 01/01/2019/ - 31/12/2022

  • PI, National Natural Science Foundation of China (NSFC) – General Project, Tracking pattern of amino acids underlying seasonal influenza, 01/01/2015 – 31/12/2018

Selected Publications

  1. Xiaoxuan Xia, William K.K. Wu, Sunny H. Wong, Dabin Liu, Thomas N.Y. Kwong, Geicho Nakatsu, Pearlly S. Yan, Yu-Ming Chuang, Michael W.Y. Chan, Olabisi O. Coker, Zigui Chen, Yun K. Yeoh, Liuyang Zhao, Xiansong Wang, Wing Y. Cheng, Matthew T.V. Chan, Paul K.S. Chan, Joseph J.Y. Sung, Maggie H Wang*, Jun Yu* (2020) (co-corresponding author) Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer. Microbiome. IF=10.465, Rank 7/149 in Microbiology

  2. Chan MC, Wang MH, Chen Z, Hui DS, Kwok AK, Yeung AC, Liu KM, Yeoh YK, Lee N, Chan PK. Frequent Genetic Mismatch between Vaccine Strains and Circulating Seasonal Influenza Viruses, Hong Kong, China, 1996–2012. Emerging infectious diseases. (2018) Oct;24(10):1825. IF = 8.22. Rank 3/84

  3. Maggie Haitian Wang*, Haoyi Weng+, Rui Sun, Jack Lee, William Ka Kei Wu, Ka Chun Chong, Benny Chung-Ying Zee (2017) A Zoom-Focus Algorithm (ZFA) to locate the optimal testing region for rare variant association tests. Bioinformatics, IF=7.2. Corresponding author

  4. Maggie Haitian Wang, Rui Sun, Junfeng Guo, Haoyi Weng, Jack Lee, Inchi Hu, Pak Sham and Benny Chung-Ying Zee (2016). A fast and powerful W-test for pairwise epistasis testing. Nucleic Acids Research. IF=11.6.

  5. Rui Sun, Haoyi Weng, Inchi Hu, Junfeng Guo, William K.K. Wu, Benny Chung-Ying Zee, Maggie Haitian Wang* (2016) A W-test collapsing method for rare variant association testing in exome sequencing data. Genetic Epidemiology. DOI: 10.1002/gepi.22000.

  6. Maggie Haitian Wang*, Billy Chang, Rui Sun, Inchi Hu, Marc Ka Chun Chong, Benny Chung Ying Zee (2017), A Stratified Polygenic Risk Prediction Model with Application on CAGI Bipolar Disorder Sequencing Data. Human Mutation. 2017 Sep;38(9):1235-9. Rank 24/171 in Genetics & Heredity Science. IF=5.359. https://doi.org/10.1002/humu.23229

  7. Maggie Haitian Wang*, Heather Cordell, Kristel Van Steen (2019) Statistical Methods for Genome-wide Association Studies. Seminars in Cancer Biology. 2019 April. Rank 13/223 in Oncology. IF = 10.198 Doi: 10.1016/j.semcancer.2018.04.008

  8. Xiaoxuan Xia, Haoyi Weng, Rui Sun, Ka Chun Chong, Benny Chung Ying Zee*, Maggie Haitian Wang* Incorporating methylation genome information improves prediction accuracy for drug treatment responses. BMC Genetics. 2018 Sep;19(1):78. IF = 2.569 Doi: 10.1186/s12863-018-0644-5 (supervisor of the first author)

  9. Maggie Haitian Wang+, Ka Chun Chong+, Hau Yin Chung, Malina Storer, John Pickering, Zoltan Endre, Steven Lau, Chloe Kwok, Maria Lai, Benny Zee (2016). Use of a Least Absolute Shrinkage and Selection Operator (LASSO) Model to Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) Analysis of Exhaled Breath to Predict the Efficacy of Dialysis. Journal of Breath Research 10 (2016) 046004.

  10. Maggie Haitian Wang, Shaw-Hwa Lo, Tian Zheng and Inchi Hu (2012) A Classification Method Incorporating Interactions among Variables for High-dimensional Data. Bioinformatics (2012) 28 (21): 2834-2842

Last Updated: 22 July 2020

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